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Autosampler Vials & Caps
Clear and amber 9-425 screw-thread vials with matching caps and septa for HPLC, GC, and GC-MS. Screw, crimp, and snap-cap formats.
9-425
Thread Standard
1.5–2 mL
Volume Range
Screw Top, 8-425, Amber Autosampler Vials, Patch, 2mL, 100/unit
SKU: VAV-08-1020
Screw Top, 10-425, Amber Autosampler Vials, Patch, 2mL, 100/unit
SKU: VAV-10-1020
Screw Top, 13-425, Amber Autosampler Vials, Patch, 4mL, 100/unit
SKU: VAV-13-1040
Crimp Top, 11mm, Clear Autosampler Vials, Patch, 2mL, 100/unit
SKU: VCV-11-1020
Crimp Top, 11mm, Amber Autosampler Vials, Patch, 2mL, 100/unit
SKU: VDV-11-1020
Screw Top, 8-425, Clear Autosampler Vials, Patch, 2mL, 100/unit
SKU: VLV-08-1020
Screw Top, 9-425, Clear Autosampler Vials, Patch, 2mL, 100/unit
SKU: VLV-09-1020
Screw Top, 10-425, Clear Autosampler Vials, Patch, 2mL, 100/unit
SKU: VLV-10-1020
Screw Top, 13-425, Clear Autosampler Vials, Patch, 4mL, 100/unit
SKU: VLV-13-1040
Snap Top, 11mm, Clear Autosampler Vials, Patch, 2mL, 100/unit
SKU: VNV-11-1020
Snap Top, 11mm, Amber Autosampler Vials, Patch, 2mL, 100/unit
SKU: VSV-11-1020
Screw Top, 9-425, Amber Autosampler Vials, Patch, 2mL, 100/unit
SKU: VAV-09-1020
9mm, Conical Bottom Inserts, 0.25mL, 100/unit
SKU: VJC-09-0002
9mm, Flat Bottom Inserts, 0.3mL, 100/unit
SKU: VJF-09-0003
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Selecting the Right Autosampler Vial
Autosampler vials are the final container between sample preparation and instrument injection. The right vial protects sample integrity and ensures consistent chromatographic results. Clear glass (Type 1 Class A borosilicate) is the default for most HPLC and GC analyses. Amber glass provides UV protection for light-sensitive analytes such as vitamins, PAHs, and certain pharmaceuticals. Choose your closure type based on your autosampler model: screw-thread (9-425) for most Agilent, Waters, and Shimadzu systems; crimp for headspace GC; and snap-cap for high-throughput labs needing fast capping.
VIAL SELECTION GUIDE
Closure types compared
| Closure | Thread / Size | Seal Type | Best For | Key Advantage |
|---|---|---|---|---|
| Screw Cap | 9-425 thread | PTFE/Silicone septum | HPLC, LC-MS, GC (liquid injection) | Easy open/close, reusable, most universal |
| Crimp Cap | 11mm / 13mm | PTFE/Silicone or Butyl septum | Headspace GC, volatile analysis | Hermetic seal prevents analyte loss |
| Snap Cap | 11mm snap-on | PTFE/Silicone septum | High-throughput HPLC screening | Fastest capping, no tools needed |
💡Quick Selection Tips
Low-volume samples? Use a micro-insert (100-300 uL) inside a standard 2 mL vial to reduce dead volume and improve recovery. Volatile analytes? Crimp caps with PTFE/butyl septa provide the best seal integrity for headspace and purge-and-trap GC. EPA methods? Our 20 mL and 40 mL VOA vials with open-top caps and PTFE-lined septa meet EPA 524.2, 624, and 8260 requirements.
COMMON QUESTIONS
Autosampler Vials FAQ
Use amber vials when your analytes are photosensitive. This includes PAHs, certain pesticides, vitamins (especially A, D, E, K), retinoids, and some pharmaceutical compounds. Amber glass blocks UV light below approximately 450 nm. For most routine HPLC and GC work with non-photosensitive analytes, clear glass is preferred because it allows visual inspection of the sample.
PTFE/Silicone is the most versatile - the PTFE face contacts the sample (chemically inert) and the silicone back provides resealing. Use this for HPLC and GC liquid injections. PTFE/Red Rubber is economical for single-injection applications. Butyl/PTFE provides the lowest gas permeability for headspace GC and volatile organic analysis.
Our standard 2 mL, 12x32mm vials with 9-425 screw threads fit the vast majority of HPLC and GC autosamplers from Agilent, Waters, Shimadzu, Thermo, and PerkinElmer. Crimp vials (11mm) fit Agilent headspace samplers and similar models. Check your instrument manual for the required vial dimensions if unsure.
A flat-bottom insert sits in the vial with a wider base and is easier to handle, but has more dead volume. A conical (tapered) insert concentrates the sample at the bottom tip, reducing dead volume and improving recovery for samples under 100 uL. Use conical inserts with spring bottoms for the best results with limited-volume samples.
Yes. We offer convenience kits with pre-assembled vials, septa, and caps ready to fill. This saves time in high-volume labs and ensures consistent septa orientation. Available in both clear and amber glass with your choice of closure type.
Setting up a new chromatography lab?
We can help you spec the right vials, caps, and inserts for your instruments and methods. Volume pricing available for case quantities.