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Filter Vials
Integrated filter vials that combine sample filtration and storage in a single device. Eliminate the syringe filter step and reduce dead volume for HPLC and UHPLC workflows.
3+
Membrane Types
0.2-0.45µm
Pore Sizes
Snap Top, 0.22um, Low Evap Filter Vials, Pre-Slit, PTFE, 0.48mL, 100/unit
SKU: FVP-B2-0020
PTFE · 0.22um
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What Are Filter Vials?
Filter vials integrate a membrane filter directly into an autosampler vial, allowing you to filter and collect your sample in one step. Press the plunger to push sample through the built-in membrane, then load the vial directly onto your HPLC or UHPLC autosampler. This eliminates the need for separate syringe filters and transfer steps, reducing dead volume and minimizing sample loss.
COMPARISON GUIDE
Thomson Filter Vials vs. Traditional Syringe Filtration
| Feature | Thomson Filter Vial | Syringe + Filter + Vial |
|---|---|---|
| Steps Required | 1 (press plunger) | 3 (draw, attach filter, push into vial) |
| Dead Volume | < 10 µL | 50–150 µL (filter + syringe) |
| Sample Recovery | > 98% | 85–95% |
| Risk of Contamination | Minimal (closed system) | Higher (open transfer) |
| Cost per Filtration | Moderate (all-in-one) | Higher (3 disposables) |
| Membranes Available | PTFE, Nylon, PES | PTFE, Nylon, PES, PVDF, MCE, GF |
💡Best Practice
When working with aqueous samples, use PES or Nylon membrane filter vials. For organic solvents and aggressive mobile phases, choose PTFE. Always verify chemical compatibility with your specific solvent system before processing a full batch.
FREQUENTLY ASKED
Filter Vial FAQ
Use 0.45 µm for standard HPLC columns (>3 µm particle size) and 0.2 µm for UHPLC columns (≤2 µm particle size). Smaller pore sizes provide better protection against particulate damage to sub-2-micron column packing.
For most analytical workflows involving HPLC, UHPLC, and ion chromatography, yes. Filter vials are ideal for small sample volumes (0.1–1.5 mL). For larger volumes or vacuum-driven filtration, traditional syringe filters or membrane disc filters are still preferred.
Thomson filter vials use a standard 12 x 32mm format compatible with most major autosampler platforms including Waters, Agilent, Shimadzu, and Thermo Fisher. Verify your autosampler tray dimensions before ordering.
Use PES (polyethersulfone) filter vials for protein-containing samples. PES has the lowest protein binding among common membranes, maximizing analyte recovery. Avoid PTFE for aqueous protein solutions as it is hydrophobic.
Load at least 200–300 µL of sample to ensure sufficient filtrate volume for injection. The dead volume in the filter assembly is approximately 10 µL, so nearly all loaded sample is recoverable.
Switching from syringe filters to filter vials?
Our technical team can recommend the right membrane and pore size for your specific HPLC or UHPLC application.