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CHROMODORIS ANNAE
Chromatography Vials
Autosampler vials, headspace vials, scintillation vials, VOA vials, filter vials, caps, septa, and inserts for HPLC, GC, LC-MS, and environmental analysis.
6 Types
Vial Categories
Certified
Low Extractables
Matched
Cap + Septum Sets
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Matching Vials to Your Instrument and Method
Your vial choice depends on your instrument autosampler and analytical method. Autosampler vials (2mL, 9mm or 11mm) are the standard for HPLC, UHPLC, and LC-MS. Headspace vials (10–20mL) are used with headspace-GC for volatile analysis. VOA vials (40mL) are required by EPA methods for drinking water and wastewater volatiles. Always match the cap closure type (crimp, snap, or screw) to your autosampler tray.
VIAL TYPE GUIDE
Which vial type fits your method?
| Vial Type | Volume | Closure | Method / Instrument |
|---|---|---|---|
| Autosampler | 2 mL | Crimp, Snap, Screw (9mm/11mm) | HPLC, UHPLC, LC-MS, GC |
| Filter Vials | 0.5–1 mL filtrate | Press-fit plunger | HPLC, LC-MS (sample + filter in one) |
| Headspace | 10–20 mL | Crimp, Screw (18mm/20mm) | Headspace-GC, GC-MS (volatiles) |
| VOA | 40 mL | Screw (24-400) | EPA 524.2, 624.1 (water volatiles) |
| Scintillation | 20 mL | Screw (22mm) | Liquid scintillation counting, storage |
| Inserts | 100–400 µL | Sits inside 2mL vial | Low-volume HPLC/LC-MS samples |
💡Septum Material Matters
PTFE/Silicone — universal choice, chemically inert, reseals well. PTFE/Red Rubber — economical, single-injection use. Pre-slit PTFE — reduces needle coring for sensitive LC-MS work. For headspace analysis, use butyl rubber septa to prevent volatile loss. Always check that your septum thickness matches your autosampler needle stroke.
COMMON QUESTIONS
Chromatography Vials FAQ
Crimp caps are crimped onto the vial with a tool — most secure seal, best for volatiles and LC-MS. Snap caps push on by hand — fastest to use, good for HPLC. Screw caps thread on — easy to open/close, reusable. Your autosampler tray determines which type you need.
Use amber vials for light-sensitive compounds (photodegradable drugs, vitamins, some pesticides). Clear vials are fine for most applications and let you visually inspect your sample before injection.
Use inserts when your sample volume is too small to reach the needle tip in a standard 2mL vial (typically below 500µL). Inserts sit inside the vial and position your small-volume sample where the needle can reach it.
Yes. Our 40mL VOA vials with PTFE-lined caps meet the requirements of EPA Methods 524.2, 524.4, and 624.1 for volatile organic compound analysis in water. Certified clean vials are available for trace-level work.
Need help matching vials to your instrument?
Tell us your autosampler model and we'll recommend the right vial, cap, and septum combination.