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Sealing Membranes & Films
Adhesive and heat-seal films for PCR plates. Optical, foil, and peelable options for qPCR, storage, and sample transport.


Aluminum Plate Seal, Sealing Membrane, 100/unit
SKU: PCM-31-0096


Plate Seal, Bio-Rad, Sticky Adhesive, Sterile, 100/unit
SKU: PCM-11-B096


Plate Seal, Pressure Adhesive, 100/unit
SKU: PCM-21-0096
Sealing Solutions for PCR and Storage
The right seal prevents evaporation, eliminates cross-contamination between wells, and ensures optical clarity for fluorescence detection. We carry adhesive films for quick manual application, heat-seal foils for automated sealing, and peelable films for plates that need to be accessed multiple times.
Adhesive vs. heat-seal films
| Seal Type | Application | Optical | Temp Range | Best For |
|---|---|---|---|---|
| Optical Adhesive | Manual press | Yes — optically clear | −40°C to 110°C | qPCR, real-time detection through the seal |
| Foil Adhesive | Manual press | No — opaque | −80°C to 110°C | Sample storage, DMSO-containing plates |
| Heat-Seal Foil | Heat sealer required | No — opaque | −80°C to 110°C | Automated workflows, long-term storage, shipping |
| Peelable Adhesive | Manual press | Varies | −40°C to 80°C | Multi-access plates, compound libraries, re-sealing |
Optical adhesive films must be completely flat and bubble-free across all wells for consistent fluorescence readings. Use a plate roller or applicator paddle to ensure uniform contact. Any trapped air creates optical artifacts that increase well-to-well variability in Ct values.
Sealing Film FAQ
Yes. Our adhesive films are rated for thermal cycling up to 110°C and will maintain their seal through 40+ PCR cycles. Ensure the heated lid makes full contact with the film surface for optimal performance.
Yes. Heat-seal foils require a plate heat sealer (typically 170–180°C, 2–3 seconds). The resulting seal is stronger than adhesive and better suited for long-term storage, shipping, and DMSO-containing samples that can dissolve adhesive films.
Use aluminum foil seals (adhesive or heat-seal) for plates containing DMSO. DMSO is a solvent that can dissolve or weaken polyester-based optical adhesive films over time, leading to evaporation and cross-contamination.
Peelable films can be partially peeled back and re-sealed for multi-access applications like compound library cherry-picking. However, each peel-reseal cycle slightly reduces adhesion. For plates accessed more than 3–4 times, apply a fresh seal.